La maladie de Parkinson au Canada (serveur d'exploration)

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Effects of dark-rearing on the retinal dopaminergic system in the neonatal and postnatal guinea pig

Identifieur interne : 004717 ( Main/Exploration ); précédent : 004716; suivant : 004718

Effects of dark-rearing on the retinal dopaminergic system in the neonatal and postnatal guinea pig

Auteurs : Arthur W. Spira [Canada] ; David Parkinson [États-Unis]

Source :

RBID : ISTEX:46190F9FDEB83B5767D52F2C04CC6E51A13A717C

English descriptors

Abstract

To appraise the extent of light responsivity of the retinal dopaminergic system in the early postnatal period, dopamine content (DA) of retinas of cycling-light-reared and dark-reared guinea pigs was determined. DA storage postnatally was suppressed in dark-reared animals. Their retinas responded to a brief light stimulus by rapidly increasing DOPA synthesis and DA utilization, but not to the extent of the response of cycling-light-reared animals. Dopaminergic retinal neurones depend on light stimulus for the complete development of some of their neurochemical characteristics.

Url:
DOI: 10.1016/0165-3806(91)90200-3


Affiliations:


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Le document en format XML

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